Polynucleotides
Advanced Skin Regeneration Through Collagen Stimulation
At KAST Medical Aesthetics, we believe healthy, youthful-looking skin starts with skin quality. Rather than simply correcting the visible signs of ageing, Polynucleotides work by stimulating your skin’s natural repair processes to improve its strength, hydration and resilience from within.
As we age, collagen and elastin production naturally declines, causing the skin to become thinner, less elastic and more prone to fine lines, crepiness and dehydration. Polynucleotide treatments encourage the production of new collagen, helping to restore healthier, firmer and more radiant skin over time.
The result is gradual, natural-looking rejuvenation that enhances the quality of your skin without adding volume or changing your facial features.
What Are Polynucleotides?
Polynucleotides are highly purified DNA fragments that act as powerful biostimulators within the skin. Once injected, they stimulate fibroblast cells, encouraging the production of collagen and elastin while supporting the skin’s natural repair and regeneration processes.
Unlike treatments that restore lost volume or relax facial muscles, Polynucleotides focus on improving the health and quality of the skin itself. At KAST Medical Aesthetics, we use the PhilArt® Polynucleotide range, including specialist formulations for the face, eyes, scalp and body.

Why Are Polynucleotides Different?
Polynucleotides are part of a new generation of regenerative aesthetic treatments that work with your body’s natural healing processes rather than masking the signs of ageing.
Unlike dermal fillers, they do not add volume, and unlike anti-wrinkle treatments, they do not affect muscle movement. Instead, they stimulate collagen production and tissue repair, creating healthier, stronger skin that continues to improve over time.
Many patients choose Polynucleotides because they want subtle, natural-looking rejuvenation with long-term improvements in skin quality.

How Do Polynucleotides Work?
Following treatment, Polynucleotides stimulate fibroblast activity within the skin, encouraging the production of collagen and elastin. As the skin regenerates, patients often notice improvements in:
- Skin quality and texture
- Hydration
- Elasticity and firmness
- Fine lines and wrinkles
- Crepey skin
- Overall skin radiance
- Skin strength and resilience
Because the treatment works by stimulating regeneration, results develop gradually over the weeks following treatment.

Who Are Polynucleotides Suitable For?
Polynucleotides are ideal for patients looking to improve skin quality without adding volume or altering their natural facial features.
Treatment may be suitable for concerns including:
- Fine lines and wrinkles
- Dull or dehydrated skin
- Loss of elasticity
- Crepey skin
- Early skin laxity
- Dark circles around the eyes
- Thinning hair and scalp health
A consultation allows us to assess your skin and determine whether Polynucleotides are the most appropriate treatment for your goals.

Areas That Can Be Treated
One of the advantages of Polynucleotides is their versatility. Treatment can be used across multiple areas of the face and body, including:
- Face
- Under-eye area
- Neck
- Décolletage
- Hands
- Body
- Scalp
Every treatment plan is tailored to your individual concerns following a detailed consultation.

Polynucleotides for the Eye Area
The delicate skin around the eyes is often one of the first areas to show signs of ageing. Using PhilArt® Eye, Polynucleotides can help improve fine lines, crepey skin, dark circles and overall skin quality around the eyes.
By stimulating collagen production within this delicate area, treatment helps create a brighter, smoother and more refreshed appearance while maintaining natural-looking results.

Polynucleotides for Hair & Scalp Health
Polynucleotides can also be used within the scalp to support healthier hair growth and improve scalp condition.
Treatment works by creating a healthier environment for the hair follicles, helping to strengthen existing hair, improve scalp health and support healthier hair growth. It can be suitable for both men and women experiencing hair thinning.

Personalised Treatment Planning
Every Polynucleotide treatment begins with a comprehensive consultation.
We’ll assess your skin quality, treatment history, degree of collagen loss and long-term goals before creating a personalised treatment plan. Some patients achieve excellent results with Polynucleotides alone, while others benefit from combining them with complementary treatments.
Where appropriate, Polynucleotides can be incorporated into a wider regenerative treatment plan alongside treatments such as JULÄINE™, skin boosters, microneedling, dermal fillers and medical-grade skincare.
Our focus is always on achieving healthier, stronger skin through gradual, natural-looking improvement.
What to Expect From Treatment
Following your consultation, Polynucleotides are carefully injected into the selected treatment area using advanced techniques designed to maximise comfort, precision and safety.
Treatment usually takes around 30 to 45 minutes, depending on the area being treated. Mild redness, swelling or small bumps at the injection sites are normal and usually settle within a few days. Most patients are able to return to their normal daily activities shortly afterwards.
You’ll also receive personalised aftercare advice to help support your recovery and achieve the best possible results.
When Will I See Results?
Because Polynucleotides stimulate collagen production rather than adding immediate volume, results develop gradually.
Many patients notice improvements in hydration and skin quality within the first few weeks, with continued improvements in firmness, elasticity and texture over the following months as new collagen forms.
For the best outcome, we typically recommend a course of three treatments, performed around three weeks apart, followed by maintenance treatments every three to six months, depending on your individual skin concerns.
FAQs
Are Polynucleotides the same as dermal fillers?
No. Dermal fillers restore lost volume, whereas Polynucleotides improve the quality, strength and health of the skin by stimulating natural collagen production.
How many treatments will I need?
Most patients benefit from a course of three treatments, followed by maintenance sessions every three to six months.
When will I see results?
Many patients notice early improvements in skin hydration within a few weeks, with continued improvements over the following two to three months.
Can Polynucleotides treat the eye area?
Yes. We use specialist PhilArt® Eye Polynucleotides to improve concerns such as fine lines, crepey skin and dark circles around the eyes.
Can Polynucleotides be combined with other treatments?
Absolutely. Polynucleotides are often incorporated into personalised treatment plans alongside JULÄINE™, skin boosters, microneedling, dermal fillers and medical-grade skincare to achieve comprehensive skin rejuvenation.
Treatment price list
Book Your Polynucleotide Consultation
If you’re looking to improve your skin quality, firmness and overall skin health, Polynucleotides offer an advanced regenerative approach to facial rejuvenation.
Our experienced team will assess your concerns, discuss your goals and create a personalised treatment plan tailored to your skin and long-term aesthetic objectives.
Book your Polynucleotide consultation at KAST Medical Aesthetics today.
All treatments are subject to a satisfactory consultation. Terms and Conditions apply.
